Analytical Chemistry

Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a highly sensitive analytical technique used for elemental analysis. In ICP-MS, the purity of the sample introduction system, including water, is crucial for accurate and precise determination of trace elements. High-purity water is essential to minimize matrix effects, interferences, and ensure reliable results in elemental analysis.

What Is The Impact Of Water On ICP-MS?

The quality of water directly influences the performance of ICP-MS. Impurities in water can introduce spectral interferences, affect sensitivity, and lead to inaccurate quantification of trace elements, compromising the reliability of elemental analysis.

What Types Of Contaminants In Water Can Affect ICP-MS Results?

Water impurities that can impact ICP-MS results include:

Ionic Contaminants

Impact:

Elevated levels of metal ions can interfere withICP-MS analyses.

Effect:

Excess metal ions may contribute to background signals, affecting the sensitivity and accuracy of mass measurements. In quantitative analyses, interference from ions can lead to inaccuracies in the determination of metal concentrations.

Organic Contaminants

Impact:

The presence of organic impurities can affect the accuracy of ICP-MS results.

Effect:

Unintended organic compounds may lead to matrix effects, influencing the reliability of trace metal analyses. In environmental monitoring, for example, interference from organics can compromise the accuracy of metal concentration measurements.

Particulates

Impact:

Presence of particulate matter in ICP-MS samples can cause blockages.

Effect:

Particulates may lead to fluctuations in the aerosol generation process, affecting the reproducibility of measurements. Thisinterference can compromise the precision of ICP-MS analyses.

Water Measurement Requirements for ICP-MS

In Inductively Coupled Plasma Mass Spectrometry (ICP-MS), the accurate and sensitive detection of trace metals is paramount.The quality of water used in sample preparation can significantly impact the results by introducing contaminants. For applications demanding high precision and minimal interference in the analysis of trace metals, the use of apyrogenic, ultrapure Type 1 water is strongly recommended.

Water Quality Standards According to Industry Guidelines:

Method

Resistivity (MΩ.cm)*

TOC (ppb)

Filter (μm)

Bacteria (CFU/ml)

Endotoxins (EU/ml)

Nucleases

ICP-MS

18.2

<10

<0.2

ICP-OES

>18.0

<10

<0.2

Method

ICP-MS

Resistivity (MΩ.cm)*

18.2

TOC (ppb)

<10

Filter (μm)

<0.2

Bacteria (CFU/ml)

Endotoxins (EU/ml)

Nucleases

Method

ICP-OES

Resistivity (MΩ.cm)*

>18.0

TOC (ppb)

<10

Filter (μm)

<0.2

Bacteria (CFU/ml)

Endotoxins (EU/ml)

Nucleases

Adhering to these water quality standards is crucial for achieving accurate and reproducible results in ICP-MS analyses. Type I water is recommended for applications requiring the highest level of sensitivity, while Type Il water may be suitable for routine analyses.

NOTES:

If removal of finer particulates (< 0.05 micron) is required, consider upgrading to CLS-5400 series systems.

CLS-3200

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CLïR 3200 High Purity Lab Water System with UV Oxidation

25.25

⅜" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 10 CFU / ml

< 1ppb

< 5 ppb

Countertop, Wall Mount

Electrochemistry, Gas Chromatography Mass Spectrometry (GC/MS), High Performance Liquid Chromatography (HPLC), Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Trace Organics

Analytical Chemistry

CLS-5200-R-1-TOC

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CLïR 5200 Ultrapure Lab Water System with TOC Monitoring & UV Oxidation (Remote 120V)

14.4

21.6

14.7

⅜" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

< 5 ppb

2.5

Wall Mount, Remote Dispense

Electrochemistry, Gas Chromatography Mass Spectrometry (GC/MS), High Performance Liquid Chromatography (HPLC), Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Trace Organics

Analytical Chemistry

CLS-5200-R-2-TOC

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CLïR 5200 Ultrapure Lab Water System with TOC & UV Oxidation (Remote 220V)

14.4

21.6

14.7

⅜" O.D. Tubing

220V/50Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

< 5 ppb

2.5

Wall Mount, Remote Dispense

Electrochemistry, Gas Chromatography Mass Spectrometry (GC/MS), High Performance Liquid Chromatography (HPLC), Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Trace Organics

Analytical Chemistry

CLS-5200-S-1-TOC

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CLïR 5200 Ultrapure Lab Water System with TOC Monitor & UV Oxidation (Standard 120V)

14.4

21.6

14.7

½" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

< 5 ppb

2.5

Countertop

Electrochemistry, Gas Chromatography Mass Spectrometry (GC/MS), High Performance Liquid Chromatography (HPLC), Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Trace Organics

Analytical Chemistry

System

Label

System Depth (in)

System Height (in)

System Width (in)

Dry Weight (lbs)

Inlet Connection

System Voltage

TOC Monitoring

0.05μ Ultrafiltration

Ultraviolet Oxidation

Effluent Purity

Effluent Microorganisms

Effluent Sodium

Effluent Chlorides

Effluent TOC

System Maximum
Output (lpm)

Volumetric Presets

Mounting

Laboratory Applications

CAtegory

CLS-3200

Get a quote

Download Spec Sheet

CLïR 3200 High Purity Lab Water System with UV Oxidation

25.25

⅜" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 10 CFU / ml

< 1ppb

< 5 ppb

Countertop, Wall Mount

Electrochemistry, Gas Chromatography Mass Spectrometry (GC/MS), High Performance Liquid Chromatography (HPLC), Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Trace Organics

Analytical Chemistry

CLS-5200-R-1-TOC

Get a quote

Download Spec Sheet

CLïR 5200 Ultrapure Lab Water System with TOC Monitoring & UV Oxidation (Remote 120V)

14.4

21.6

14.7

⅜" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

< 5 ppb

2.5

Wall Mount, Remote Dispense

Electrochemistry, Gas Chromatography Mass Spectrometry (GC/MS), High Performance Liquid Chromatography (HPLC), Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Trace Organics

Analytical Chemistry

CLS-5200-R-2-TOC

Get a quote

Download Spec Sheet

CLïR 5200 Ultrapure Lab Water System with TOC & UV Oxidation (Remote 220V)

14.4

21.6

14.7

⅜" O.D. Tubing

220V/50Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

< 5 ppb

2.5

Wall Mount, Remote Dispense

Electrochemistry, Gas Chromatography Mass Spectrometry (GC/MS), High Performance Liquid Chromatography (HPLC), Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Trace Organics

Analytical Chemistry

CLS-5200-S-1-TOC

Get a quote

Download Spec Sheet

CLïR 5200 Ultrapure Lab Water System with TOC Monitor & UV Oxidation (Standard 120V)

14.4

21.6

14.7

½" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

< 5 ppb

2.5

Countertop

Electrochemistry, Gas Chromatography Mass Spectrometry (GC/MS), High Performance Liquid Chromatography (HPLC), Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Trace Organics

Analytical Chemistry

The difference is CLïR.

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Applications

Analytical Chemistry

Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

What Is The Impact Of Water On ICP-MS?

Ionic Contaminants

Organic Contaminants

Particulates

Water Measurement Requirements for ICP-MS

Method

Resistivity (MΩ.cm)*

TOC (ppb)

Filter (μm)

Bacteria (CFU/ml)

Endotoxins (EU/ml)

Nucleases

Method

Resistivity (MΩ.cm)*

TOC (ppb)

Filter (μm)

Bacteria (CFU/ml)

Endotoxins (EU/ml)

Nucleases

System

Label

System Depth (in)

System Height (in)

System Width (in)

Dry Weight (lbs)

Inlet Connection

System Voltage

TOC Monitoring

0.05μ Ultrafiltration

Ultraviolet Oxydation

Effluent Purity

Effluent Microorganisms

Effluent Sodium

Effluent Chloride

Effluent TOC

System MaximumOutput (lpm)

Volumetric Presets

Mounting

Laboratory Applications

CAtegory

System

Label

System Depth (in)

System Height (in)

System Width (in)

Dry Weight (lbs)

Inlet Connection

System Voltage

TOC Monitoring

0.05μ Ultrafiltration

Ultraviolet Oxydation

Effluent Purity

Effluent Microorganisms

Effluent Sodium

Effluent Chloride

Effluent TOC

System MaximumOutput (lpm)

Volumetric Presets

Mounting

Laboratory Applications

CAtegory

System

Label

System Depth (in)

System Height (in)

System Width (in)

Dry Weight (lbs)

Inlet Connection

System Voltage

TOC Monitoring

0.05μ Ultrafiltration

Ultraviolet Oxidation

Effluent Purity

Effluent Microorganisms

Effluent Sodium

Effluent Chlorides

Effluent TOC

System Maximum
Output (lpm)

System Maximum
Output (lpm)

System Maximum
Output (lpm)

System Maximum
Output (lpm)

System Maximum
Output (lpm)

System Maximum
Output (lpm)