Genetic Chemistry

Genetics

Genetics encompasses the study of genes, heredity, and genetic variations. In genetic research and applications such as gene expression analysis and genetic engineering, the quality of water is critical for various processes, including DNA/RNA extraction, PCR, and sequencing. High-purity water is essential to prevent interference with genetic materials and ensure reliable results in genetic experiments.

What Is The Impact Of Water In Genetics?

Water quality plays a crucial role in genetic experiments. Contaminated water can introduce impurities into genetic samples, affect enzymatic reactions, and compromise the accuracy of genetic analyses. High-purity water is necessary to maintain the integrity of genetic materials and ensure the success of genetic experiments.

What Types Of Contaminants In Water Can Affect Genetics?

Water impurities that can impact genetic experiments include:

Bacteria & Microorganisms

Impact:

Bacterial contamination can adversely affect genetic studies.

Effect:

Unintended microorganisms may introduce variations in genetic samples, leading to inconsistencies in experimental conditions and compromising the reliability of genetic analyses. This can affect the accuracy of DNA or RNA studies.

Endotoxins

Impact:

Endotoxins can affect the integrity of genetic material.

Effect:

In genetic experiments, endotoxins may lead to changes in DNA or RNA structure, affecting the accuracy of genetic analyses. This can compromise the reliability of results in molecular biology studies.

Organic Compounds

Impact:

Small organic compounds in water can introduce unwanted signals in genetic assays.

Effect:

Organic impurities, such as humic acids and pesticides, may affect the purity of genetic samples. Removal of these organic compounds from genetic buffers is crucial to ensure accurate and reliable genetic results.

Ionic Contaminants

Impact:

Ionic contaminants can interfere with genetic analyses.

Effect:

Elevated levels of ions may affect the stability of DNA or RNA structures, leading to variations in genetic results. Maintaining low levels of ionic contaminants is essential for the reproducibility and accuracy of genetic analyses.

Water Measurement Requirements for Genetics

Genetic chemistry applications demand a high level of water purity to ensure the accuracy of genetic analyses. The choice of water type is driven by the sensitivity of the genetic methods employed. For techniques requiring precision and reliability, such as polymerase chain reaction (PCR) and genetic sequencing, the use of apyrogenic, ultrapure Type 1 water is strongly recommended.

Water Quality Standards According to Industry Guidelines:

Resistivity (MΩ.cm)*

>18

TOC (ppb)

<10

Filter (μm)

<0.2

Bacteria (CFU/ml)

Endotoxins (EU/ml)

<0.002

Nucleases

Not detected

Resistivity (MΩ.cm)*

TOC (ppb)

Filter (μm)

Bacteria (CFU/ml)

Endotoxins (EU/ml)

Nucleases

>18

<10

<0.2

<0.002

Not detected

Adhering to these water quality standards is crucial for the success and accuracy of genetic experiments. Type I water is recommended for critical genetic applications, while Type II water may be suitable for routine experiments.

NOTES:

Applications requiring Endotoxin filtration should purchase a CLF-5000-02E Endotoxin removal final filter.

CLS-3400

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CLïR 3400 High Purity Lab Water System with 0.05 Micron Ultrafiltration and UV

25.25

⅜" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 10 CFU / ml

< 1ppb

< 5 ppb

Countertop, Wall Mount

DNA Sequencing, Forensics, Genetics, Molecular Biology, Polymerase Chain Reaction (PCR)

Genetic Chemistry

CLS-5400-R-1-TOC

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CLiR 5400 Ultrapure Lab Water System with TOC Monitoring, UV Disinfection & Ultrafiltration (Remote 120v)

14.4

21.6

14.7

⅜" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

Wall Mount, Remote Dispense

DNA Sequencing, Forensics, Genetics, Molecular Biology, Polymerase Chain Reaction (PCR)

Genetic Chemistry

CLS-5400-R-2-TOC

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CLiR 5400 Ultrapure Lab Water System with TOC Monitoring, UV Disinfection & Ultrafiltration (Remote 220v)

14.4

21.6

14.7

⅜" O.D. Tubing

220V/50Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

Wall Mount, Remote Dispense

DNA Sequencing, Forensics, Genetics, Molecular Biology, Polymerase Chain Reaction (PCR)

Genetic Chemistry

CLS-5400-S-1-TOC

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CLiR 5400 Ultrapure Lab Water System with TOC Monitoring, UV Disinfection & Ultrafiltration (Standard 120v)

14.4

21.6

14.7

⅜" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

Countertop

DNA Sequencing, Forensics, Genetics, Molecular Biology, Polymerase Chain Reaction (PCR)

Genetic Chemistry

System

Label

System Depth (in)

System Height (in)

System Width (in)

Dry Weight (lbs)

Inlet Connection

System Voltage

TOC Monitoring

0.05μ Ultrafiltration

Ultraviolet Oxidation

Effluent Purity

Effluent Microorganisms

Effluent Sodium

Effluent Chlorides

Effluent TOC

System Maximum
Output (lpm)

Volumetric Presets

Mounting

Laboratory Applications

CAtegory

CLS-3400

Get a quote

Download Spec Sheet

CLïR 3400 High Purity Lab Water System with 0.05 Micron Ultrafiltration and UV

25.25

⅜" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 10 CFU / ml

< 1ppb

< 5 ppb

Countertop, Wall Mount

DNA Sequencing, Forensics, Genetics, Molecular Biology, Polymerase Chain Reaction (PCR)

Genetic Chemistry

CLS-5400-R-1-TOC

Get a quote

Download Spec Sheet

CLiR 5400 Ultrapure Lab Water System with TOC Monitoring, UV Disinfection & Ultrafiltration (Remote 120v)

14.4

21.6

14.7

⅜" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

Wall Mount, Remote Dispense

DNA Sequencing, Forensics, Genetics, Molecular Biology, Polymerase Chain Reaction (PCR)

Genetic Chemistry

CLS-5400-R-2-TOC

Get a quote

Download Spec Sheet

CLiR 5400 Ultrapure Lab Water System with TOC Monitoring, UV Disinfection & Ultrafiltration (Remote 220v)

14.4

21.6

14.7

⅜" O.D. Tubing

220V/50Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

Wall Mount, Remote Dispense

DNA Sequencing, Forensics, Genetics, Molecular Biology, Polymerase Chain Reaction (PCR)

Genetic Chemistry

CLS-5400-S-1-TOC

Get a quote

Download Spec Sheet

CLiR 5400 Ultrapure Lab Water System with TOC Monitoring, UV Disinfection & Ultrafiltration (Standard 120v)

14.4

21.6

14.7

⅜" O.D. Tubing

120V/60Hz

> 18 MΩ/cm

< 1 CFU/ml

< 1ppb

Countertop

DNA Sequencing, Forensics, Genetics, Molecular Biology, Polymerase Chain Reaction (PCR)

Genetic Chemistry

The difference is CLïR.

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Applications

Genetic Chemistry

Genetics

What Is The Impact Of Water In Genetics?

Bacteria & Microorganisms

Endotoxins

Organic Compounds

Ionic Contaminants

Water Measurement Requirements for Genetics

Resistivity (MΩ.cm)*

TOC (ppb)

Filter (μm)

Bacteria (CFU/ml)

Endotoxins (EU/ml)

Nucleases

System

Label

System Depth (in)

System Height (in)

System Width (in)

Dry Weight (lbs)

Inlet Connection

System Voltage

TOC Monitoring

0.05μ Ultrafiltration

Ultraviolet Oxydation

Effluent Purity

Effluent Microorganisms

Effluent Sodium

Effluent Chloride

Effluent TOC

System MaximumOutput (lpm)

Volumetric Presets

Mounting

Laboratory Applications

CAtegory

System

Label

System Depth (in)

System Height (in)

System Width (in)

Dry Weight (lbs)

Inlet Connection

System Voltage

TOC Monitoring

0.05μ Ultrafiltration

Ultraviolet Oxydation

Effluent Purity

Effluent Microorganisms

Effluent Sodium

Effluent Chloride

Effluent TOC

System MaximumOutput (lpm)

Volumetric Presets

Mounting

Laboratory Applications

CAtegory

System

Label

System Depth (in)

System Height (in)

System Width (in)

Dry Weight (lbs)

Inlet Connection

System Voltage

TOC Monitoring

0.05μ Ultrafiltration

Ultraviolet Oxydation

Effluent Purity

Effluent Microorganisms

Effluent Sodium

Effluent Chloride

Effluent TOC

System MaximumOutput (lpm)

Volumetric Presets

Mounting

Laboratory Applications

Laboratory Applications

CAtegory

System

System Maximum
Output (lpm)

System Maximum
Output (lpm)

System Maximum
Output (lpm)

System Maximum
Output (lpm)

System Maximum
Output (lpm)

System Maximum
Output (lpm)